Huntington Potter, PhD

Director of Alzheimer’s Research, Linda Crnic Institute for Down Syndrome
Department of Neurology, University of Colorado Denver

Dr. Huntington Potter is Professor of Neurology and Director of Alzheimer’s Disease Research in the Department of Neurology and the Linda Crnic Center for Down Syndrome at the University of Colorado, Denver. He discovered and is devoted to studying the mechanistic relationship between Alzheimer’s Disease and Down syndrome. Recognizing that these disorders are two sides of the same coin and studying them together will best hasten the development of new treatments for both. Read more about Dr. Huntington Potter’s groundbreaking research.

Prior to joining UC Denver, Dr. Potter studied, researched and taught for 30 years at Harvard University. He received his AB Cum Laude in Physics and Chemistry and his MA and PhD in Biochemistry and Molecular Biology before spending 13 years on the faculty of the Neurobiology Department. In 1998, he joined the Faculty at the University of South Florida as the Eric Pfeiffer Chair for Research on Alzheimer’s Disease. He designed and directed the NIA-designated Florida Alzheimer’s Disease Research Center at USF and was elected President of the Faculty at the College of Medicine, and President of the USF Tampa Faculty Senate. From 2004-2008, he was CEO and Scientific Director of the Johnnie B. Byrd Sr. Alzheimer’s Center & Research Institute, during which time the Institute built the largest free-standing Alzheimer’s disease research institute in the world and developed 7 new treatments for Alzheimer’s disease in preparation for human trials, before joining USF.

Dr. Potter is credited with the first demonstration of the Holliday intermediate in genetic recombination, the perfection of electroporation for gene transfer, and the discovery of the essential role of inflammation and the amyloid-promoting activity of the apoE-4 protein in Alzheimer’s disease. He also discovered that Alzheimer’s disease and Down syndrome, which invariably leads to Alzheimer’s by age 30-40, are mechanistically related to each other and to cancer through the development of cells with abnormal numbers of chromosomes, which will be the focus of his research at UC Denver. He is author of over 100 scientific articles and books, is the holder of 15 U.S. and foreign patents, has sat on scientific advisory and review committees in academia, industry and government, and has received numerous awards for his work.  In 2010, Dr. Potter was elected a Fellow of the American Association for the Advancement of Science.  His electron micrographs of DNA are on permanent exhibit in the National American History Museum of the Smithsonian Institute in Washington D.C.