Webinarios GLOBALES
New Clinical Trials Targeting Alzheimer’s Disease
in People with Down Syndrome
Tuesday, April 8, 2025
12pm – 1:15pm MT
GLOBAL Webinars are an important benefit for our Members. Held quarterly, these 1+ hour-long webinars cover topics across the lifespan. Webinars are FREE for GLOBAL Members and $10/webinar for non-Members. If you have a family member or dear friend with Down syndrome, this webinar is for you!
In this session, Dr. Rafii will discuss:
- Why people with Down syndrome are at high risk for developing Alzheimer’s disease
- Information about how to get involved in clinical trials for Alzheimer’s disease in people with Down syndrome
Michael S. Rafii, MD, PhD
Dr. Rafii is a board-certified neurologist, Professor of Clinical Neurology at the Keck School of Medicine and Medical Director of the Alzheimer’s Therapeutic Research Institute (ATRI).
Dr. Rafii is a physician-scientist whose research focuses on developing treatments for Alzheimer’s disease (AD) including a genetic form of AD that occurs in people with Down syndrome (DS). He is Principal Investigator of the NIH-funded Alzheimer’s Clinical Trials Consortium – Down Syndrome (ACTC-DS), an international network of over 20 expert sites conducting clinical trials for Alzheimer’s in people with Down syndrome. Dr. Rafii’s work has been featured in the New York Times, Chicago Tribune, Washington Post, Wall Street Journal and on National Public Radio (NPR).
Save The Date – Upcoming Webinars
Tuesday, August 5, 2025
Neurodiversity and Individuals with Down Syndrome
Nicole Baumer, MD
In case you missed it…
Stopping the Autoimmune Attack in Down Syndrome: New Breakthroughs and Clinical Trials
Dr. Joaquin Espinosa
How to Manage Swallowing Issues in Children with Down Syndrome
Dr. Emily DeBoer, Arwen Jackson, & Jennifer Maybee
What Families Need to Know! A Pediatrician’s Tips for Understanding Common Lab Results
Dr. Kishore Vellody
Ya está disponible la versión adaptada a las familias de nuestra innovadora Guía mundial de cuidados médicos para adultos con síndrome de Down.
PARA FAMILIAS:
Request Printed Copies!
PARA CLÍNICOS:
Download Our Version for
Medical Professionals Today
GLOBAL WEBINARS – MAKING AN IMPACT
8,343
Individuals Educated
49
Expert Speakers
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States Participated
54
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65,000+
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Q&A WITH OUR EXPERTS – A VALUABLE MEMBERSHIP BENEFIT
SLEEP APNEA ACROSS THE LIFESPAN
IN PEOPLE WITH DOWN SYNDROME
Q: How does one define moderate vs severe sleep apnea? What percent in oxygen saturation during OSA episodes is the average range?
A: They are defined based on the obstructive apnea hypopnea index, which is the number of obstructive episodes during sleep divided by the hours of sleep. Many patients experience drops in oxygen saturation during obstructive episodes. These drops are variable and range from very mild to severe down to 60-70%.
DOWN SYNDROME REGRESSION DISORDER: THE LATEST RESEARCH AND PROMISING TREATMENTS
Q: What age are you seeing regression symptoms starting?
A: I think that when we’ve looked at our population level data, the mean age at onset is about 18. We see a heavy clustering in the late teen years, early twenties, and the reason why we’ve come up with this particular age range is because younger than 10, the chances that this may be autism or some other biochemical or genetic phenomenon is much higher. And similarly, over 30 is where we start to kind of bridge that gap into early onset Alzheimer’s, although that is still very young.
Your Library of GLOBAL Webinars & Experts
ACROSS THE LIFESPAN
Arvind Hoskoppal, MD
Congenital Heart Disease: What You Need to Know Through the Lifespan
ACROSS THE LIFESPAN
Joaquín Espinosa, PhD
Stopping the Autoimmune Attack in Down Syndrome: New Breakthroughs and Clinical Trials
ACROSS THE LIFESPAN
Dr. Emily DeBoer, Arwen Jackson & Jennifer Maybee
How to Manage Swallowing Issues in Children with Down Syndrome
ACROSS THE LIFESPAN
Dr. Kishore Vellody
What Families Need to Know! A Pediatrician’s Tips for Understanding Common Lab Results
ACROSS THE LIFESPAN
Dr. Joaquín Espinosa
An Important Update on Groundbreaking Clinical Trials & Research for People with Down Syndrome
ACROSS THE LIFESPAN
Drs. Leonard Abbeduto & Angela Thurman
ACROSS THE LIFESPAN
Drs. Ignacio Tapia & Rachel Whelan
Apnea del sueño a lo largo de la vida en personas con síndrome de Down
ACROSS THE LIFESPAN
Drs. Steven Perlman & Marc Ackerman
Dental Care Across the Lifespan of Patients with Down Syndrome
ACROSS THE LIFESPAN
Drs. Joaquín Espinosa & Jonathan Santoro
Down Syndrome Regression Disorder: The Latest Research and Promising Treatments
PEDIATRIC
Dr. Nicole Baumer, MEd
ACROSS THE LIFESPAN
Drs. Emily McCourt & Michael Puente
Eye Research & Eye Care for Individuals with Down Syndrome Across the Lifespan
PEDIATRIC
Drs. Lina Patel & Debbie Fiddler
Executive Function Skills in Everyday Life: From Research to Intervention
ACROSS THE LIFESPAN
Dr. Joaquín Espinosa
PEDIATRIC
Dr. Karen Remley
How the CDC Supports People with Down Syndrome & An Update on COVID-19 Vaccinations
TEEN & ADULT
Dr. Sarah Mann
Strength, Stability, Balance, and Endurance: Purposeful PT for Teens and Adults with Down Syndrome
ADULT
Dr. Brian Chicoine & Guideline Co-Authors
ACROSS THE LIFESPAN
Dr. Lina Patel, PsyD
CPAP, Hearing Aids, & Glasses, Oh My! How to Help my Child & Adult Wear their Medical Equipment
PEDIATRIC
Dr. Francis Hickey
Pediatric Medical Care Guidelines for Down Syndrome: What Families Need to Know
ACROSS THE LIFESPAN
Michelle Sie Whitten, MA & Kevin Brennan
Self-Advocates Win Landmark Federal Funding for Research: Join GLOBAL – Join the Movement
ACROSS THE LIFESPAN
Dr. Michael Yeager
Take A Deep Breath: Lung Infection & Cognition in Down Syndrome
PEDIATRIC
Patricia C. Winders, PT
ADULT
Dr. Huntington Potter & Bryn Gelaro, LSW
Supporting Aging Adults with Down Syndrome and Alzheimer’s Disease
PEDIATRIC
Sie Center Specialists
Developing an Individualized Feeding Plan for Your Child with Down Syndrome
ACROSS THE LIFESPAN
Dr. Joaquín Espinosa
ADULT
Dr. Dennis McGuire & Bryn Gelaro, LSW
Promoting Skills to Survive & Thrive in the Teen & Adult Years
PEDIATRIC
Kathleen Mays, MS, CCC-SLP
Multimodal Approach to Teaching Children with Down syndrome Speech & Language Skills
Important Notice
The Global Down Syndrome Foundation’s employees and/or volunteers are NOT acting as your medical professional or attorney. Responses you receive via electronic mail, phone, or in any other manner DO NOT create or constitute a doctor-patient or attorney-client relationship between you and the Global Down Syndrome Foundation (GLOBAL), or any employee of, or other person associated with, GLOBAL.
Information received from GLOBAL’s employees or volunteers, or from this website, should NOT be considered a substitute for the advice of a medical professional or lawyer. GLOBAL DOES NOT provide any medical or legal advice. You should consult with your own doctor or lawyer for medical or legal advice. This website is a general service that provides information over the internet. The information contained on this website is general information and should not be construed as medical advice to be applied to any specific factual situations.
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